Dutch CF Registry 2017 - Symptoms and consequences

Bacterial and fungal infections

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People with CF suffer from bacterial and fungal infections due to the disturbed water-salt balance. Because of the tougher mucus in the lungs, bacteria and fungi stick to the mucus. Patients with CF can therefore suffer from (chronic) bacterial or fungal infections for a long time. In 2017, 52% of adults and 13% of children had a chronic infection with the Pseudomonas aeruginosa bacteria.
A chronic infection can cause the pulmonary function to deteriorate, which in turn negatively affects the patient’s prognosis. 




Figure 1 below shows in which age category of patients with CF bacterial and fungal infections are most or least prevalent.

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One way to try to combat a chronic infection is to use inhalation antibiotics, antibiotics that you inhale into the lungs. See Medication for the respiratory and digestive tracts for more information.